Biopharmaceutical Products
Lentiviral vectors have become important tools in gene therapy, offering new opportunities for treating a wide array of diseases. Learn more about comparison with AAVs and how lentiviral vector manufacturing challenges – from plasmid design to aseptic filling and controlled freezing – can be solved to enhance overall manufacturing efficiency.
Brian Moloney
November 5, 2024
Biopharmaceutical Products
Oligonucleotide manufacturing. Optimizing fluid management, freezing & cold storage | Purification Oligonucleotides
Michael Mühlegger
October 25, 2024
Biopharmaceutical Products
What are oligonucleotides? Nucleic acid types | RNA oligonucleotides | DNA oligos | Types of Oligonucleotides
Michael Mühlegger
October 25, 2024
Biopharmaceutical Products
Freezing cells is a process that requires more than simply placing them in a freezer with dimethyl sulfoxide (DMSO). It is a precise and meticulous process, where precision and expertise are essential. The goal is to achieve high cell viability and therefore high yield for cell-based therapies or cell banking.
Khalil Essani
October 11, 2024
Biopharmaceutical Products
This article explores the challenges posed by RNase contamination and the solutions that can be employed to mitigate these risks. RNase contamination | Ribonuclease inhibitors | RNase-free equipment
David Seifert
August 13, 2024
Biopharmaceutical Products
RNase contamination can lead to the degradation of RNA, thereby compromising the efficacy of RNA-based drugs. Types of RNase | RNase and DNase | Role of DEPC
David Seifert
August 12, 2024
Biopharmaceutical Products
Ensuring that cell and gene therapy products are shipped at cold temperatures with robust controls is even more important for cell & gene therapies than it is for more traditional biopharmaceutical products.
Michael Mühlegger
July 8, 2024
Biopharmaceutical Products
In biosimilar production, fluid management takes on an overarching role, as it is encountered at several manufacturing steps. This is all the more reason to deal with efficiency in fluid management – which we will do in this article.
Brian Moloney
May 14, 2024
Biopharmaceutical Products
The manufacturing process of biosimilars is a complex endeavor, accompanied by several challenges. We will discuss some of the biggest hurdles in this article, along with solutions to overcome them.
Brian Moloney
May 14, 2024
Biopharmaceutical Products
The development process of biosimilars slightly differs from the one of their reference biologics. In this article, we will discuss each phase in detail.
Michael Eder
May 13, 2024
Biopharmaceutical Products
As biologics have become a central pillar in today’s healthcare sector, their manufacturing process increasingly draws attention. In this article, we will discuss the process step by step, including challenges and possible ways to overcome them.
Michael Eder
May 13, 2024
Biopharmaceutical Products
Establishing both efficient and safe manufacturing processes for biosimilars requires planning, expertise, and state-of-the-art equipment. In this article, we will shed light on different steps in the manufacturing process and discuss ways to improve them.