Biopharmaceutical Products
Proper handling of viral vectors during storage, freezing, and thawing is crucial to maintaining their integrity and efficacy. In this article, we will explore best practices for preserving viral vectors, ensuring their stability, and maximizing their potential for various applications.
Alexander Fuchs
September 20, 2023
Biopharmaceutical Products
Viral vectors like Adeno-associated viruses (AAVs) are popular vectors for gene therapy and vaccines. And yet, there is product loss due to leakages of primary packagings or other mishandling of fluids. In order to deliver high-quality and viable products efficiently, safe handling experience a growing interest.
Claus Exenberger
September 20, 2023
Biopharmaceutical Products
In this blog post, we'll show examples of AAVs as gene therapy vectors and examine the tangible results of FDA-approved AAV gene therapies, which offer actual solutions and hope for patients affected by genetic disorders.
Michael Mühlegger
September 19, 2023
Biopharmaceutical Products
The main difference between adeno-associated viral vectors (AAV) and adenoviral vectors (AVV) is their genetic makeup. AAV is composed of a single-stranded DNA viral vector, while adenoviral vectors consist of double-stranded DNA.
Michael Mühlegger
September 19, 2023
Biopharmaceutical Products
Various types of viral vectors are central to genetic research and medical advancements. These small carriers, obtained from various viruses, play an essential role in gene therapy and beyond. In this exploration, we will examine different types, the applications, unique attributes, and the complex terrain of producing viral vectors.
Michael Mühlegger
September 19, 2023
Biopharmaceutical Products
The adeno-associated virus (AAV) is a very popular viral vector with great potential available for gene delivery. This article explores AAV vectors, their role in gene therapy, and their associated advantages and disadvantages.
Khalil Essani
September 18, 2023
Biopharmaceutical Products
In this article, we will give an overview of the pDNA manufacturing market – not only taking a look at the dry figures, but also highlighting the services that are offered by important plasmid DNA manufacturing companies.
Daniel Tischler
September 13, 2023
Biopharmaceutical Products
Plasmid DNA fulfills several functions in bacteria, but they are also widely used in the biopharma sector. In this article, we will uncover their key functions.
Michael Mühlegger
September 13, 2023
Biopharmaceutical Products
The pDNA manufacturing process is multifaceted yet essential in the biopharmaceutical industry. Here, we will describe the process step by step.
Michael Mühlegger
September 12, 2023
Biopharmaceutical Products
Plasmids are part of the genetic material in bacteria, complementing chromosomal DNA with additional functions. But there is much more to plasmids, as you can read in this article.
Michael Mühlegger
September 7, 2023
Biopharmaceutical Products
Plasmid DNA is not only found in bacteria, but also ubiquitous in biotechnology. In this article, we have collected 7 interesting facts on pDNA.
Michael Mühlegger
September 7, 2023
Biopharmaceutical Products
Single Use Support unveils its latest customized innovation within the product range of automated of biopharmaceutical manufacturing, RoSS.FILL. With its unmatched precision and cutting-edge technology, RoSS.FILL CGT is a game-changer for the cell and gene therapy industry.
Brian Moloney
August 22, 2023
Articles by Biopharmaceutical Products:
Articles by Manufacturing Processes:
E-Book
In this publication we show that the initial price can be deceiving and there are significant additional costs during ongoing usage in the long term. Plate freezers ensure a complete, consistent, and fast freezing (and thawing) to ensure the quality of your high-valued drug substance is maintained, and through simple lifecycle analysis they outpace conventional options regarding total costs.
E-Book
Homogeneity of pharmaceuticals plays a major role in fluid management. Liquid drugs have different viscosities, degrees of sedimentation, and other varying properties, making it difficult to standardize the aliquotation of liquids. RoSS.PADL is a homogenizing solution with kneading and cooling functions for standardizing the mixing of biopharmaceuticals precedenting the dispensation into single-use bioprocess containers. This fully automated and hence standardized process ensures homogeneous distribution of the liquids in single-use bio process containers.
E-Book
This guide for bioconjugate manufacturing with regards to fluid and cold chain management addresses challenges such as: protection against ADC toxicity, accuracy in fluid management, maintaining ADC stability after freeze-thaw cycles, transition from lab to commercialization, and cost considerations of equipment.
