Biopharmaceutical Products
As the demand for messenger RNA-based products continues to rise, efficient fluid management plays a crucial role in ensuring the high-quality production of mRNA drug products. This article is about challenges and the latest advancements in fluid management techniques, focusing on filling, filtering, and aliquoting mRNA during the manufacturing process.
Brian Moloney
June 29, 2023
Biopharmaceutical Products
The use of lipid nanoparticles has gained significant attention due to their potential applications in drug delivery systems. In this article we explore the process of filling and aliquoting LNPs in single-use bags and highlight its significance and key considerations.
Brian Moloney
June 28, 2023
Biopharmaceutical Products
Freezing is a significant process step in the manufacturing of LNP-based products. In this article, we will therefore take a look at the impact freezing has on lipid nanoparticles.
Alexander Fuchs
June 26, 2023
Biopharmaceutical Products
Being promising tools in life sciences and medicine, lipid nanoparticles are drawing attention on their manifold advantages. In this article, however, we take a step back and discover how LNPs are produced. Solutions based on single-use systems for increasing quality and efficiency in production are also covered.
Brian Moloney
June 21, 2023
Biopharmaceutical Products
Lipid nanoparticles (LNPs) have shown to bring several benefits to research and therapy. This article, however, focuses on concerns on LNP toxicity and ways o address them.
Daniel Tischler
June 19, 2023
Biopharmaceutical Products
Lipid nanoparticles are highly valued tools in the field of mRNA delivery, making them essential for various therapeutic and research approaches. In this article, we will take a look at the pros and cons of LNPs in mRNA delivery.
Michael Mühlegger
June 17, 2023
Biopharmaceutical Products
New advances in mRNA technology are happening regularly and rapidly. The prevention and treatment of viruses and immunogenic diseases has become possible through new therapeutics that use messenger RNA to help the body produce specific proteins. Nevertheless, the heightened demand for mRNA drugs leads to challenges for its production.
Daniel Tischler
June 15, 2023
Biopharmaceutical Products
Non-viral vectors play an increasingly important role in biomedical research and therapy, including gene therapy. In this article, we will discuss the role of non-viral vectors for this specific purpose.
Michael Mühlegger
June 13, 2023
Biopharmaceutical Products
Lipid nanoparticles are multifunctional tools used in a variety of different applications, supporting mRNA as a valuable instrument in medicine and research. In this article, we will shed light on what the different applications of LNPs are.
Daniel Tischler
June 6, 2023
Biopharmaceutical Products
ADCs can be described as a new rising star among biopharmaceutics. They are able to specifically target and destroy cancer cells very effectively. Their levels of toxicity can vary depending on several factors, including their specific design and the potency of the cytotoxic drug. This is why safe handling in between facilities is such an important issue and must not be taken lightly.
Brian Moloney
May 9, 2023
Biopharmaceutical Products
Bioconjugates are powerful tools in several areas of life sciences and beyond. In this article, we will have a look at the technology in general as well as at examples of bioconjugates in specific fields.
Michael Eder
April 26, 2023
Biopharmaceutical Products
Depending on their constituents, ADCs are extremely variable and can be used for several, very distinct purposes. In this article, we will present you 5 examples of ADCs and their respective characteristics.
Brian Moloney
April 25, 2023
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E-Book
In this publication we show that the initial price can be deceiving and there are significant additional costs during ongoing usage in the long term. Plate freezers ensure a complete, consistent, and fast freezing (and thawing) to ensure the quality of your high-valued drug substance is maintained, and through simple lifecycle analysis they outpace conventional options regarding total costs.
E-Book
Homogeneity of pharmaceuticals plays a major role in fluid management. Liquid drugs have different viscosities, degrees of sedimentation, and other varying properties, making it difficult to standardize the aliquotation of liquids. RoSS.PADL is a homogenizing solution with kneading and cooling functions for standardizing the mixing of biopharmaceuticals precedenting the dispensation into single-use bioprocess containers. This fully automated and hence standardized process ensures homogeneous distribution of the liquids in single-use bio process containers.
E-Book
This guide for bioconjugate manufacturing with regards to fluid and cold chain management addresses challenges such as: protection against ADC toxicity, accuracy in fluid management, maintaining ADC stability after freeze-thaw cycles, transition from lab to commercialization, and cost considerations of equipment.
