Biopharmaceutical Products
The preservation of cells at cryogenic temperature can be achieved using different techniques. This is far from a simple freezing process; it's a carefully controlled method that prevents the formation of ice crystals, thus maintaining the integrity of the biological material.
Brian Moloney
August 11, 2023
Biopharmaceutical Products
In research, medicine and biotechnology, cell viability is an elementary parameter and Critical Quality Attribute (CQA). In this article, we will present you 7 facts regarding the term, related concepts, improvement possibilities and more.
Brian Moloney
August 10, 2023
Biopharmaceutical Products
Cryopreservation is essential to maintain ex vivo viability of organic materials – indispensable, for instance, in fields like cell banking. In this article, we will explore central aspects of this technique.
Brian Moloney
August 10, 2023
Biopharmaceutical Products
Cell viability is a fundamental parameter in cell-based biopharma processing and cell banking. Therefore, it is essential not only to measure cell viability, but also to take measures for its improvement. Learn more in this article.
Michael Eder
July 31, 2023
Biopharmaceutical Products
Although there are significant differences between cytotoxicity and cell viability, they both are frequent concepts in cell biology and cell banking. We will discuss these two parameters in this article.
Michael Mühlegger
July 26, 2023
Biopharmaceutical Products
Both cell viability and cell proliferation are important parameters in cell banking. In this article, we will shed light on these two concepts.
Michael Eder
July 26, 2023
Biopharmaceutical Products
mRNA is the acronym for messenger ribonucleic acid – but there is much more to know about this fascinating molecule, as it is essential in elementary biological processes. In this article, we will give readers a brief explanation of what mRNA actually is and discuss its application in medicine as well as recent advances in mRNA technology.
Michael Eder
July 6, 2023
Biopharmaceutical Products
In order for the genetic information encoded by DNA to become an accessible blueprint for protein production, mRNA is indispensable. In this article, we will provide a comprehensive definition of mRNA and illustrate its main functions.
Michael Eder
July 6, 2023
Biopharmaceutical Products
mRNA is a fundamental component of several biological processes, and its unique properties are used in different fields of medicine and research. mRNA manufacturing, however, is a complicated endeavor. In this article, we will take a detailed look at mRNA manufacturing and the advantages that come with single-use technologies.
Daniel Tischler
July 5, 2023
Biopharmaceutical Products
Meeting the temperature requirements of mRNA-based products is essential to maintain product efficiency and safety. Effective mRNA cold chain management is necessary, but comes with several challenges. In this article, we will discuss relevant considerations and innovative solutions in mRNA cold chain management.
Michael Eder
July 5, 2023
Biopharmaceutical Products
Considering the manifold applications of mRNA, it is essential to establish optimal freezing processes that maintain viability and effectiveness. In this article, we will compare different freezing methods for mRNA.
Alexander Fuchs
July 4, 2023
Biopharmaceutical Products
After the first LNPs were approved by FDA in 2018, the whole field of LNPs as drug delivery systems has expanded rapidly. In the following article we will explore what qualifies lipid nanoparticles as one of the most promising pharmaceutical drug delivery systems and will take a closer look at their structure, applications and challenges connected with the manufacturing process.
Michael Mühlegger
June 30, 2023
Articles by Biopharmaceutical Products:
Articles by Manufacturing Processes:
E-Book
In this publication we show that the initial price can be deceiving and there are significant additional costs during ongoing usage in the long term. Plate freezers ensure a complete, consistent, and fast freezing (and thawing) to ensure the quality of your high-valued drug substance is maintained, and through simple lifecycle analysis they outpace conventional options regarding total costs.
E-Book
Homogeneity of pharmaceuticals plays a major role in fluid management. Liquid drugs have different viscosities, degrees of sedimentation, and other varying properties, making it difficult to standardize the aliquotation of liquids. RoSS.PADL is a homogenizing solution with kneading and cooling functions for standardizing the mixing of biopharmaceuticals precedenting the dispensation into single-use bioprocess containers. This fully automated and hence standardized process ensures homogeneous distribution of the liquids in single-use bio process containers.
E-Book
This guide for bioconjugate manufacturing with regards to fluid and cold chain management addresses challenges such as: protection against ADC toxicity, accuracy in fluid management, maintaining ADC stability after freeze-thaw cycles, transition from lab to commercialization, and cost considerations of equipment.
