Biopharmaceutical Products
Autologous therapies and other ATMPs with small volumes exhibit certain specific requirements. The scope of handling advanced therapies require special handling and care. When handling of small volumes is already automated in an early stage, it is a way more straightforward path to commercialization of the drug product. The benefit of a closed systems with automated solutions add value by offering a higher degree of sterility, safety, and process flexibility.
Brian Moloney
December 4, 2023
Biopharmaceutical Products
With adeno-associated virus being a popular viral vector, along with a growing interest in gene therapies, there is an increased need for cost-effective vector manufacturing technologies and viral vector production platforms for human gene therapy products.
Khalil Essani
November 19, 2023
Biopharmaceutical Products
Considering the widespread need for efficient pDNA production, the industry is seeking to improve the current manufacturing process. In this article, we will discover how single-use technologies can contribute to pDNA manufacturing optimizations.
Khalil Essani
November 10, 2023
Biopharmaceutical Products
The challenges in viral vector production are many. The manufacturing process is complex and often demands more flexibility than traditional techniques and devices can offer. Read more!
Brian Moloney
October 21, 2023
Biopharmaceutical Products
Packaging AAVs is crucial as a method to encapsulate a gene of interest within a viral vector. Therefore, we will discuss related methods and services in this article.
Michael Eder
September 21, 2023
Biopharmaceutical Products
This article will discuss several aspects of viral vector vaccines: We will uncover seven intriguing facts that shed light on this technology: From the ability to mimic infections to the challenges of storage and the diverse applications and more.
Brian Moloney
September 21, 2023
Biopharmaceutical Products
When designing gene therapies, the choice between non-viral and viral vectors plays an important role in determining the success and safety of therapeutic interventions. Non-viral vectors offer unique advantages, while viral vectors have their own set of strengths and weaknesses. In this blog post, we will explore the types, benefits, and limitations of both non-viral and viral vectors in gene therapy.
Khalil Essani
September 21, 2023
Biopharmaceutical Products
Gene therapy holds the promise of revolutionizing medical treatments by harnessing the power of viral vectors to deliver therapeutic genes into the genome of patients. In this blog post, we will illustrate these facets of viral vectors in gene therapy in detail.
Khalil Essani
September 21, 2023
Biopharmaceutical Products
Viral vector manufacturing involves advanced biotechnological methods, with scalability being one of the major difficulties. In this article, we will discuss both challenges and innovative approaches for viral vector production.
Khalil Essani
September 20, 2023
Biopharmaceutical Products
There are several differences, but also a few significant similarities between viral vector vaccines and non-viral-vector based mRNA vaccines – we will uncover them in this article.
Michael Mühlegger
September 20, 2023
Biopharmaceutical Products
Viral vectors have become an indispensable tools in therapeutic and research applications. In this article, we will provide a broad overview of this fascinating topic.
Michael Mühlegger
September 20, 2023
Biopharmaceutical Products
In this article, we uncover the significance of a professional aliquotation process, the challenges entailed in filling viral vectors like AAVs, and the innovative solutions supporting to master those challenges.
Brian Moloney
September 20, 2023
Articles by Biopharmaceutical Products:
Articles by Manufacturing Processes:
E-Book
In this publication we show that the initial price can be deceiving and there are significant additional costs during ongoing usage in the long term. Plate freezers ensure a complete, consistent, and fast freezing (and thawing) to ensure the quality of your high-valued drug substance is maintained, and through simple lifecycle analysis they outpace conventional options regarding total costs.
E-Book
Homogeneity of pharmaceuticals plays a major role in fluid management. Liquid drugs have different viscosities, degrees of sedimentation, and other varying properties, making it difficult to standardize the aliquotation of liquids. RoSS.PADL is a homogenizing solution with kneading and cooling functions for standardizing the mixing of biopharmaceuticals precedenting the dispensation into single-use bioprocess containers. This fully automated and hence standardized process ensures homogeneous distribution of the liquids in single-use bio process containers.
E-Book
This guide for bioconjugate manufacturing with regards to fluid and cold chain management addresses challenges such as: protection against ADC toxicity, accuracy in fluid management, maintaining ADC stability after freeze-thaw cycles, transition from lab to commercialization, and cost considerations of equipment.
