Cell & Gene Therapy

Stay updated with the latest breakthroughs in cell and gene therapy through our expert-written articles. Discover how these therapies are revolutionizing modern medicine. Single Use Support provides robust solutions for the secure transport and storage of cell and gene therapy products, ensuring they maintain their efficacy.

Featured Articles

Small batch manufacturing in fill-finish for cell and gene therapy

Cell & Gene Therapy

Small batch manufacturing & fill-finish in cell and gene therapy

A great example is the treatment of insidious cancers with CAR T-cells, that relies on modifying the patient’s own T-cells to instill them with a targeted way to fight cancer cells. Learn more why forming strong collaborations will solve many issues!

Michael Mühlegger

October 10, 2022

Cell & Gene Therapy

Cell and gene therapy: In vivo and Ex vivo in comparison

Gene therapy is a technique that modifies a person’s genes to treat or cure disease. Ex Vivo and In Vivo are two different approaches you will learn about in this article!

Michael Mühlegger

December 2, 2021

Car t-cell therapy and it's great potential

Cell & Gene Therapy

CAR T-cell therapy - the process and side effects

Read more about CAR-T cell therapy, its history and hurdles. Learn also how Single Use Support can support this novel therapy with great potential!

Michael Eder

July 23, 2020

Newsletter subscription

Get the latest delivered directly to your inbox!

Get the latest delivered directly to your inbox! You can unsubscribe at any time, no hard feelings. Privacy policy.

All articles about Cell & Gene Therapy

Cell & Gene Therapy

DMSO: Freezing Cells

Freezing cells is a process that requires more than simply placing them in a freezer with dimethyl sulfoxide (DMSO). It is a precise and meticulous process, where precision and expertise are essential. The goal is to achieve high cell viability and therefore high yield for cell-based therapies or cell banking.

Khalil Essani

October 11, 2024

Cell & Gene Therapy

The Role of Single-Use Systems in Cell and Gene Therapies

Ensuring that cell and gene therapy products are shipped at cold temperatures with robust controls is even more important for cell & gene therapies than it is for more traditional biopharmaceutical products.

Michael Mühlegger

July 8, 2024

Freezing Mammalian Cell Line for increased CHO cell viability

Cell & Gene Therapy

Study: Optimizing Cell Viability During CHO Cell Freezing

In a recent study, freezing protocols were tested with the RoSS.LN2F controlled liquid nitrogen freezer to find the optimal freezing rate for CHO-K1 cells in order to achieve maximum cell viability.

Alexander Fuchs

February 16, 2024

RoSS.KSET freezing single-use bags Cell Banking

Cell & Gene Therapy

Stressing Cells: The Role of Cryoprotectants in ATMP Cryopreservation

The objective of an optimal cryopreservation strategy is to deactivate (put on hold) degenerative cellular pathways and preserve proliferative potential by reducing the temperature below –130°C. To reduce the effects of ice crystal and osmotic injuries, cryopreservation protocols usually incorporate cryoprotective agents (CPAs).

Khalil Essani

February 8, 2024

Meeting cGMP standards for vaccine manufacturing

Cell & Gene Therapy

Regulations for Cryoprotectants in ATMP Cryopreservation

Adequate quality control samples retained before cell therapy treatment are a crucial component of effective regulation and need to represent the conditions and history in the cryobag. A deep dive into GMP Annex 1 on ATMP Cryopreservation.

Khalil Essani

February 7, 2024

Cell & Gene Therapy

Optimizing pDNA production using advanced single-use technologies

Considering the widespread need for efficient pDNA production, the industry is seeking to improve the current manufacturing process. In this article, we will discover how single-use technologies can contribute to pDNA manufacturing optimizations.

Khalil Essani

November 10, 2023

Cell & Gene Therapy

Plasmid DNA manufacturing companies – market overview

In this article, we will give an overview of the pDNA manufacturing market – not only taking a look at the dry figures, but also highlighting the services that are offered by important plasmid DNA manufacturing companies.

Daniel Tischler

September 13, 2023

Cell & Gene Therapy

What is the function of plasmid DNA?

Plasmid DNA fulfills several functions in bacteria, but they are also widely used in the biopharma sector. In this article, we will uncover their key functions.

Michael Mühlegger

September 13, 2023

Cell & Gene Therapy

Plasmid DNA manufacturing: The process simply explained

The pDNA manufacturing process is multifaceted yet essential in the biopharmaceutical industry. Here, we will describe the process step by step.

Michael Mühlegger

September 12, 2023

Cell & Gene Therapy

What is a plasmid?

Plasmids are part of the genetic material in bacteria, complementing chromosomal DNA with additional functions. But there is much more to plasmids, as you can read in this article.

Michael Mühlegger

September 7, 2023

Cell & Gene Therapy

Plasmid DNA – 7 facts about pDNA

Plasmid DNA is not only found in bacteria, but also ubiquitous in biotechnology. In this article, we have collected 7 interesting facts on pDNA.

Michael Mühlegger

September 7, 2023

RoSS.FILL CGT Small Volumne_Product Photo-3-min

Cell & Gene Therapy

Revolutionizing Commercial Aliquotation in Advanced Therapies

Single Use Support unveils its latest customized innovation within the product range of automated of biopharmaceutical manufacturing, RoSS.FILL. With its unmatched precision and cutting-edge technology, RoSS.FILL CGT is a game-changer for the cell and gene therapy industry.

Brian Moloney

August 22, 2023

Discover more topics

Articles by Application Area:

Articles by Solution:

Recommended Downloads

E-Book

eBook: Advancing ATMP Fluid Management

Simplifying complex process logistics in fluid and cold chain management for cell & gene therapies in small volumes

RoSS.pFTU Lab Scale - in process (4 von 9)

E-Book

App Note: "Bestcellers": Controlled Filling & Freezing of Cells

"Bestcellers": Controlled Filling & Freezing of Cells Advanced Fluid Management for Cell Culture, Freezing, Cell Banking and Cell Therapy

E-Book

App Note: Enhancing Flexibility & Accuracy With Single Use Support and Sonotec

Enhancing Process Flexibility and Filling Accuracy With Automated Filling. For low volume dispensing at a commercial scale, accuracy and repeatability are essential. To achieve a filling accuracy range of even less than ± 1 mL with the RoSS.FILL platform, Single Use Support decided to implement SONOTEC‘s SONOFLOW CO.55 V3.0 ultrasonic flow meters. Hence, RoSS.FILL users benefit from advanced process safety, flexibility, and scalability with accurate and airless volume dosing.