E-Book
eBook: Advancing ATMP Fluid Management
Simplifying complex process logistics in fluid and cold chain management for cell & gene therapies in small volumes
All articles about Cell & Gene Therapy
Cell & Gene Therapy
What is the difference between cytotoxicity and cell viability?
Although there are significant differences between cytotoxicity and cell viability, they both are frequent concepts in cell biology and cell banking. We will discuss these two parameters in this article.
Michael Mühlegger
July 26, 2023
Cell & Gene Therapy
What is cell viability and cell proliferation?
Both cell viability and cell proliferation are important parameters in cell banking. In this article, we will shed light on these two concepts.
Michael Eder
July 26, 2023
Cell & Gene Therapy
What is autologous?
The term "autologous" is most frequently found in the context of cell therapy. In this article, we will therefore take a closer look at this revolutionary therapeutic approach.
Michael Eder
April 20, 2023
Cell & Gene Therapy
What is allogeneic?
What does "allogeneic" mean, precisely? How do allogeneic cell therapies work, and what is the difference to autologous approaches? Questions like these will be answered in this article.
Michael Eder
April 19, 2023
Cell & Gene Therapy
Small batch manufacturing & fill-finish in cell and gene therapy
A great example is the treatment of insidious cancers with CAR T-cells, that relies on modifying the patient’s own T-cells to instill them with a targeted way to fight cancer cells. Learn more why forming strong collaborations will solve many issues!
Michael Mühlegger
October 10, 2022
Cell & Gene Therapy
CAR-T manufacturing: process and supply chain strategies
Mastering the complex CAR T manufacturing process and the associated supply chain challenges in the cell and gene area are the major bottlenecks during the large-scale commercialization of highly promising CAR T cell products.
Michael Eder
June 23, 2022
Cell & Gene Therapy
Gene therapy manufacturing - 5 requirements to scale up
Gene therapies have become a highly promising field of groundbreaking next generation treatment, but there are some challenges to face within the manufacturing process. Here are 5 factors that will be crucial for upscaling gene therapy manufacturing with single-use technology.
Michael Mühlegger
June 9, 2022
Cell & Gene Therapy
Autologous vs. Allogeneic Cell Therapy
Although autologous and allogeneic cell therapies share both defining methodological key elements as well as various fields of application, including most innovative cancer therapies, there are significant differences between them. Therefore, a closer look on both procedures shall be presented.
Brian Moloney
May 18, 2022
Cell & Gene Therapy
Safety & Speed: handling two major factors in CAR T-cell therapy
In order to allow for a smooth and functioning process, a reliable supply chain, tailored to the specific needs of autologous therapies, is a prerequisite. Single Use Support has developed an end-to-end process solution for cell and gene therapies.
Michael Eder
January 10, 2022
Cell & Gene Therapy
Supply chain optimization in cell and gene therapies
Single Use Support is solving problems related to supply chain management through the development of smart packaging and related smart technologies for CAR T-cell therapy. Read more!
Brian Moloney
December 20, 2021
Cell & Gene Therapy
Advanced therapy medicinal products - a new era of medicine
Advanced therapy medicinal products (ATMPs) are medicines for human use that are based on genes, tissues or cells. Accordingly, they can be classified into three main types, namely gene therapy, tissue engineered- and somatic-cell therapy medicines. Read more!
Michael Eder
December 20, 2021
Cell & Gene Therapy
Cell and gene therapy: In vivo and Ex vivo in comparison
Gene therapy is a technique that modifies a person’s genes to treat or cure disease. Ex Vivo and In Vivo are two different approaches you will learn about in this article!
Michael Mühlegger
December 2, 2021
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Articles by Biopharmaceutical Products:
- Cell & Gene Therapy
- Bioconjugates
- Nucleic Acids
- Drug Delivery
- Vaccines
- Monoclonal Antibodies
Articles by Manufacturing Processes:
Recommended Downloads
E-Book
App Note: "Bestcellers": Controlled Filling & Freezing of Cells
"Bestcellers": Controlled Filling & Freezing of Cells Advanced Fluid Management for Cell Culture, Freezing, Cell Banking and Cell Therapy
E-Book
Study: Increased CHO Cell Viability with Controlled Liquid Nitrogen Freezer
The study was conducted aiming to optimize the cryogenic freezing process of the mammalian CHO-K1 cell line with an innovative controlled rate liquid nitrogen freezer (RoSS.LN2F). The study incorporated three viability assays to comprehensively assess the impact of varying freezing rates on post-thaw cell recovery | Trypan blue | LIVE/DEAD | Fluorescence.