End-to-end solution
February 10, 2023
Why CDMOs are increasingly using single-use systems
By combining a number of benefits, single-use technologies that are compliant with cGMP and GAMP seem the perfect choice. For manufacturers of drug substances, they provide a more efficient, cost-effective, and scalable solution than stainless-steel tanks by offering.
February 10, 2023
How to choose a CDMO? 7 Considerations to be made
Choosing the right CDMO or CMO to work with is an important decision. Irrespective of which stage biopharma and pharma companies find themselves in, there are certain things to consider that are valid for any stage throughout your production process.
February 10, 2023
CDMO in Biopharma: Opportunity or risk?
Both, CDMOs and CMOs, are offering major opportunities in biopharma for startups and emerging companies as well as for established players who are approaching the limits of their manufacturing facilities or are generally looking to outsource parts of or their entire commercial production.
December 19, 2022
What is upstream and downstream processing?
Upstream and downstream processing are two steps inherent to the production of active pharmaceutical ingredients (API) used in biopharmaceuticals. The production is challenged by increasing regulation and manufacturing costs. This calls for flexible solutions, which is why a growing number of manufacturing processes utilize single-use systems
March 24, 2022
Storage Density in Biopharma Manufacturing Facilities
Single-use bags with its flat shape is predestined for stacking and offer great solutions to increase storage density on-site but also for shipment. The combination of both, single use bag and RoSS® shells (Robust Storage and Shipping) makes them a cost-effective solution, as they require little storage space. RoSS® shells are available for all sizes and suppliers of single-use bags.
March 21, 2022
Scalability of single-use drug substance production
The aim was to achieve a freezing process where the last point of freeze always happens at the same time throughout all scales. If successful, the generated freezing curves will look very similar. Temperature ramps have been used to slow down or accelerate the freezing process.
February 15, 2022
Whitepaper: How controlled freezing enables scalability
In a comprehensive study the impact of ice front growth speed on scalability of freezing protein solutions has been evaluated.
February 2, 2022
Inline buffer dilution: an agile system for downstream processes
Inline buffer dilution (IBD) is a method for on demand buffer preparation from buffer concentrates at the point of use. This article will give an overview of the inline buffer dilution process and discuss its benefits over the traditional formulation of buffer solutions.
October 21, 2021
Enabling end-to-end process solutions for bottles
The Single Use Support end-to-end process for bottles can be applied independently from bottle manufacturer, it is modular and can be topped off with services such as qualifications, after-sales service and biopharma know-how.
August 30, 2021
Does RoSS® resist vaporized hydrogen peroxide?
Infiltrating product solutions from life science companies or any other supplier into Biopharma environment is justifiably not so simple. RoSS has undergone tests to find out whether the treatment of H2O2 has any effect on the surface of all its components.
June 2, 2021
Single-use end-to-end solutions - flexible, scalable and reliable
In an extremely complex, competitive and constantly evolving sector such as the biopharmaceutical industry, flexibility is key, not least since it is an immensely varied and compliance-driven field. Learn more in this article!
September 28, 2020
The call for industrial end-to-end solutions in Biopharma has been heard
Irrespective of what industry we are talking about, the term end-to-end solution describes a principle that takes a system or service – from beginning to end – and delivers a complete functional solution.