Gain a deep understanding of viral vectors and non-viral vectors and their applications in drug delivery of gene therapies and vaccine development with our informative articles. Single Use Support offers state-of-the-art solutions for the fluid & cold chain management of viral vectors, lipid nanoparticles (LNPs) and more, maintaining their integrity and functionality.
Drug Delivery
Viral vector manufacturing involves advanced biotechnological methods, with scalability being one of the major difficulties. In this article, we will discuss both challenges and innovative approaches for viral vector production.
Khalil Essani
September 20, 2023
Drug Delivery
Non-viral vectors play an increasingly important role in biomedical research and therapy, including gene therapy. In this article, we will discuss the role of non-viral vectors for this specific purpose.
Michael Mühlegger
June 13, 2023
Drug Delivery
Lentiviral vectors have become important tools in gene therapy, offering new opportunities for treating a wide array of diseases. Learn more about comparison with AAVs and how lentiviral vector manufacturing challenges – from plasmid design to aseptic filling and controlled freezing – can be solved to enhance overall manufacturing efficiency.
Brian Moloney
November 5, 2024
Drug Delivery
With adeno-associated virus being a popular viral vector, along with a growing interest in gene therapies, there is an increased need for cost-effective vector manufacturing technologies and viral vector production platforms for human gene therapy products.
Khalil Essani
November 19, 2023
Drug Delivery
The challenges in viral vector production are many. The manufacturing process is complex and often demands more flexibility than traditional techniques and devices can offer. Read more!
Brian Moloney
October 21, 2023
Drug Delivery
Packaging AAVs is crucial as a method to encapsulate a gene of interest within a viral vector. Therefore, we will discuss related methods and services in this article.
Michael Eder
September 21, 2023
Drug Delivery
This article will discuss several aspects of viral vector vaccines: We will uncover seven intriguing facts that shed light on this technology: From the ability to mimic infections to the challenges of storage and the diverse applications and more.
Brian Moloney
September 21, 2023
Drug Delivery
When designing gene therapies, the choice between non-viral and viral vectors plays an important role in determining the success and safety of therapeutic interventions. Non-viral vectors offer unique advantages, while viral vectors have their own set of strengths and weaknesses. In this blog post, we will explore the types, benefits, and limitations of both non-viral and viral vectors in gene therapy.
Khalil Essani
September 21, 2023
Drug Delivery
Gene therapy holds the promise of revolutionizing medical treatments by harnessing the power of viral vectors to deliver therapeutic genes into the genome of patients. In this blog post, we will illustrate these facets of viral vectors in gene therapy in detail.
Khalil Essani
September 21, 2023
Drug Delivery
Viral vector manufacturing involves advanced biotechnological methods, with scalability being one of the major difficulties. In this article, we will discuss both challenges and innovative approaches for viral vector production.
Khalil Essani
September 20, 2023
Drug Delivery
There are several differences, but also a few significant similarities between viral vector vaccines and non-viral-vector based mRNA vaccines – we will uncover them in this article.
Michael Mühlegger
September 20, 2023
Drug Delivery
Viral vectors have become an indispensable tools in therapeutic and research applications. In this article, we will provide a broad overview of this fascinating topic.
Michael Mühlegger
September 20, 2023
Drug Delivery
In this article, we uncover the significance of a professional aliquotation process, the challenges entailed in filling viral vectors like AAVs, and the innovative solutions supporting to master those challenges.
Brian Moloney
September 20, 2023
Drug Delivery
Proper handling of viral vectors during storage, freezing, and thawing is crucial to maintaining their integrity and efficacy. In this article, we will explore best practices for preserving viral vectors, ensuring their stability, and maximizing their potential for various applications.
Alexander Fuchs
September 20, 2023
Articles by Biopharmaceutical Products:
Articles by Manufacturing Processes:
E-Book
Guide about Viral Vector Manufacturing | Scalability in Cell Line Development | Accuracy in Bag Aliquoting | Viscosity and Homogeneity in Liquid Transfer | Product Viability after Freezing & Thawing | Bag Breakages in viral vector storage and shipping
E-Book
A Success Story of the RoSS.FILL Automated Filling Solution that Connects Upstream, Downstream and Fill & Finish. The major technology gaps are filled by automated aseptic dispensing platforms that transfer drug substances from one process step to another, such as from downstream to fill & finish. But the proven record of aseptic filling with RoSS.FILL goes into more areas of application, including seed train intensification, bacterial fermentation, media perparation and fill finish of small volumes in single-use bags.
E-Book
Guide about navigating 5 of the most overlooked challenges in non-viral vector manufacturing with regards to fluid management challenges | Degradation and instability of LNP during freezing | Scalability concerns in exosome manufacturing | Protection against toxic solvents in peptide manufacturing | Homogenization of plasmid DNA in liquid transfer | High costs of producing non-viral vectors
