Explore our comprehensive articles on bioconjugates, such as antibody-drug conjugates, delving into the science and innovation behind this crucial biopharmaceutical technology. From the latest research trends to practical applications, we cover everything you need to know. Single Use Support offers cutting-edge solutions for the safe and efficient handling of bioconjugates to ensure product integrity.
Bioconjugates
Antibody drug conjugates (ADCs) are a rapidly growing field of interest in biopharmaceutics. In comparison to conventional chemotherapy treatments, ADCs have the potential to destroy cancerous cells without damaging healthy cells in the process. In this article we will give you an introduction to this important and rapidly growing field.
Brian Moloney
April 24, 2023
Bioconjugates
Antibody-drug conjugates might revolutionize the treatment of cancer and various other diseases. However, there are some challenges to overcome in their handling, including controlled freezing – find out more in this article!
Johannes Kirchmair
October 13, 2022
Bioconjugates
ADCs offer new, highly promising approaches in the therapy of various cancer types, and the number of approved ADCs is continuously growing. In this article, we will have a look at ADCs currently approved.
Michael Mühlegger
May 7, 2024
Bioconjugates
Scale-up and industrial production of ADCs face complications due to the high safety measures which need to be taken to guarantee product efficacy and a protected working environment for staff and manufacturers. In this article we seek out to give you an overview of the different challenges during ADC manufacturing while also introducing solutions which help to ensure aseptic production methods through single-use-technologies and end-to-end systems.
Brian Moloney
May 5, 2024
Bioconjugates
ADCs can be described as a new rising star among biopharmaceutics. They are able to specifically target and destroy cancer cells very effectively. Their levels of toxicity can vary depending on several factors, including their specific design and the potency of the cytotoxic drug. This is why safe handling in between facilities is such an important issue and must not be taken lightly.
Brian Moloney
May 9, 2023
Bioconjugates
Bioconjugates are powerful tools in several areas of life sciences and beyond. In this article, we will have a look at the technology in general as well as at examples of bioconjugates in specific fields.
Michael Eder
April 26, 2023
Bioconjugates
Depending on their constituents, ADCs are extremely variable and can be used for several, very distinct purposes. In this article, we will present you 5 examples of ADCs and their respective characteristics.
Brian Moloney
April 25, 2023
Bioconjugates
ADC technology has revolutionized several fields in medicine and research. In this article, we will shed light on this groundbreaking technology.
Daniel Tischler
April 25, 2023
Bioconjugates
Antibody drug conjugates (ADCs) are a rapidly growing field of interest in biopharmaceutics. In comparison to conventional chemotherapy treatments, ADCs have the potential to destroy cancerous cells without damaging healthy cells in the process. In this article we will give you an introduction to this important and rapidly growing field.
Brian Moloney
April 24, 2023
Bioconjugates
The safe handling of ADCs or other HPAPIs is a complex and elaborate process that requires specialized facilities and a safe, sterile environment. The filling/aliquoting step in particular calls for great care and specific equipment to ensure sterility and rule out any potential cross-contamination as well as potential harm to handling staff.
Brian Moloney
April 24, 2023
Bioconjugates
The manufacturing of bioconjugates is a complex process that involves linking a drug payload with a targeting moiety using a linker. The process is highly specific and requires careful optimization to ensure that the bioconjugate is effective and safe for use in patients. Single-use technology has revolutionized the manufacturing of bioconjugates by offering a range of benefits over traditional stainless-steel manufacturing. Therefore, this article will pay special attention to this subject.
Brian Moloney
April 24, 2023
Bioconjugates
Bioconjugation is a pharmaceutical technique that is gaining more and more importance, most of all in cancer therapy. In this article, we will provide some basic information on bioconjugation, but also discuss major challenges related to this field.
Michael Mühlegger
April 20, 2023
Bioconjugates
Since the first ADCs entered clinical trials in the 1990s, they have shown great promise in treating a variety of cancers and other diseases. However, the development of ADCs has also been marked by challenges and setbacks, including issues with efficacy, safety, and manufacturing. In this article, we will explore the history of ADCs, from their early development to the latest advances in technology and applications.
Michael Eder
April 14, 2023
Bioconjugates
The antibody-drug conjugates (ADCs) market is expected to grow significantly in the next few years. But what are the key players in this competitive landscape? Find out more in this article!
Michael Eder
November 7, 2022
Articles by Biopharmaceutical Products:
Articles by Manufacturing Processes:
E-Book
A multinational CDMO (contract development and manufacturing organization) with USD 5 billion turnover develops and manufactures pharmaceuticals that are outsourced from biotechnology companies. Based on requirements the CDMO takes full responsibility of manufacturing of drug substance, cell & gene therapies and more within the contraced period of time.
E-Book
Scalability around freezing means the ability to guarantee constant freezing kinetics on proteins (biopharmaceutical molecules) in all scales, filling volumes and loading scenarios. This guide covers how to achieve scalable freezing & thawing of biopharmaceuticals by showing What is scalability? Setup for controlled icefront growth speed Scalability results Outcomes
E-Book
This guide for bioconjugate manufacturing with regards to fluid and cold chain management addresses challenges such as: protection against ADC toxicity, accuracy in fluid management, maintaining ADC stability after freeze-thaw cycles, transition from lab to commercialization, and cost considerations of equipment.
