Freeze & Thaw

Plate freezing is a process where a product’s temperature is reduced by the means of contact with cold surfaces. Thus, a defining step in the freeze-thaw process for conservation, with several advantages for biopharma.

The global distribution of any medical substance requires more than what meets the eye. Before a vaccine can finally be shipped, it needs to be safely processed and contained. Single use technologies offer a number of advantages that cover the entire biopharmaceutical process, including development, manufacturing and logistics.

Due to increased efficiency, flexibility and cost reduction, it has become standard practice to use integrated single use freeze-thaw systems with single use bags, tubing and connectors. Find out what the reasons for this are here!

With bulk drug substances playing an increasingly important role in the pharmaceutical and biopharmaceutical industry, the need for a reliable freeze/thaw process as well as safe shipping and storage is more important than ever.
 

Test our RoSS.pFTU lab scale – the perfect freeze and thaw technology for single use bags that is completely standalone, meaning it is compatible with any established bag brand. You can rent our freeze-thaw platform for up to three months. You will be reimbursed for the rent paid if you choose to purchase the platform.

In a comprehensive study the impact of ice front growth speed on scalability of freezing protein solutions has been evaluated.

What do you need for scalable freezing of biopharmaceuticals in single-use bags? 
Check out our Scalability Guide.

In this publication we show that the intital price can be deceiving and there are significant additional costs during ongoing usage in the long term. Plate freezers ensure a complete, consistent, and fast freezing (and thawing) to ensure the quality of your high-valued drug substance is maintained, and through simple lifecylcle analysis they outpace conventional options regarding total costs.

Case - study: Comparison of the freeze/thaw processes with single use and stainless steel

In a field as sensitive as biopharmaceutical development and production, controlled processes and procedures have always played a vital role and will continue to do so. Learn more why Single-use technologies are highly flexible, scalable and on another quality level.

How x-ray views from frozen single use bags affirm plate-based freezers as spearheaded freezing technology in Biopharma

Single Use Suppport’s RoSS (robust storage and shipping) shell, composed of an outer sleeve of robust stainless-steel and an adaptive inner layer of 3D foam, contributes to a safe journey. It warrants the single-use bag’s intact arrival at its final destination, keeping its precious contents protected from biocontamination and other damages.