Freeze & Thaw

November 8, 2022

Controlling cryogenic freezing with liquid nitrogen

MIWI
Michael Wieland

To control cryogenic freezing is not an easy task, especially when liquid nitrogen is involved. To keep small molecules chemically stable and prevent chemical degradation, the right practices have to be in place. Find out everything about controlled cryogenic freezing with LN2 in this article!

October 13, 2022

Controlled freezing of ADCs

johannes-kirchmaier
Johannes Kirchmair

Antibody-drug conjugates might revolutionize the treatment of cancer and various other diseases. However, there are some challenges to overcome in their handling, including controlled freezing – find out more in this article!

August 1, 2022

Cryogenic freezing process in biopharma

barbara-m-fischer
Barbara M. Fischer

Cryopreservation is an effective procedure for the quality-preserving storage of many biomaterials. Find out what cryopreservation actually is, what has to be considered along the process and where it is applied – all summed up in this article.

July 25, 2022

Pharmaceutical cold chain management – from cold to ultra-cold: An overview of all freezing ranges

mike-marciniak
Mike Marciniak

Temperature plays a significant role in the production and distribution of several revolutionary biologics. But how does the pharmaceutical cold chain work, and what temperature ranges are most frequently chosen? You will find out in this article!

July 19, 2022

Ultra-cold freezing and storing – considerations & solutions

daniel-tischler
Daniel Tischler

Implementing cold freezing and storing in supply chains is oftentimes inevitable when dealing with certain biopharmaceuticals. Learn what the main considerations are and find out how to face related challenges.

May 18, 2022

Plate freezing: best approach for freezing biopharmaceuticals

daniel-tischler
Daniel Tischler

Plate freezing is a process where a product’s temperature is reduced by the means of contact with cold surfaces. Thus, a defining step in the freeze-thaw process for conservation, with several advantages for biopharma.

February 15, 2022

Whitepaper: How controlled freezing enables scalability

micheal-eder
Michael Eder

In a comprehensive study the impact of ice front growth speed on scalability of freezing protein solutions has been evaluated.

August 17, 2021

Best choice for cold storage of Biopharmaceuticals - A Comparison

micheal-eder
Michael Eder

What's the best choice for long-term cold storage of valuable drug substance? Comparing different Biopharma technologies.

August 9, 2021

How to achieve scalable freezing & thawing of biopharmaceuticals

micheal-eder
Michael Eder

What do you need for scalable freezing of biopharmaceuticals in single-use bags? 
Check out our Scalability Guide.

August 3, 2021

Fastest service to count on for all filling and freezing platforms

anton-reitmeir
Anton Reitmeir

A fast and accessible after-sales service bring along numerous advantages for any manufacturer of biopharmaceuticals, be it CMOs, CDMOs or developing biotech companies. Here’s an overview of the most important aspects that cover a good after-sales support.

June 29, 2021

An overview of relevant suppliers: Freeze Thaw in Biopharma

micheal-eder
Michael Eder

In order to preserve biopharmaceutical properties, bulk drug substances are commonly frozen before they are being stored or sent on their way around the globe. Read more about the players and their innovations!

May 20, 2021

Frozen storage and shipping in biopharma with RoSS

micheal-eder
Michael Eder

Single Use Suppport’s RoSS (robust storage and shipping) shell, composed of an outer sleeve of robust stainless-steel and an adaptive inner layer of 3D foam, contributes to a safe journey. It warrants the single-use bag’s intact arrival at its final destination, keeping its precious contents protected from biocontamination and other damages.