Freeze & Thaw
Temperature plays a significant role in the production and distribution of several revolutionary biologics. But how does the pharmaceutical cold chain work, and what temperature ranges are most frequently chosen? You will find out in this article!
Alexander Fuchs
July 25, 2022
Freeze & Thaw
Implementing cold freezing and storing in supply chains is oftentimes inevitable when dealing with certain biopharmaceuticals. Learn what the main considerations are and find out how to face related challenges.
Daniel Tischler
July 19, 2022
Freeze & Thaw
Plate freezing is a process where a product’s temperature is reduced by the means of contact with cold surfaces. Thus, a defining step in the freeze-thaw process for conservation, with several advantages for biopharma.
Alexander Fuchs
May 18, 2022
Freeze & Thaw
In a comprehensive study the impact of ice front growth speed on scalability of freezing protein solutions has been evaluated.
Michael Eder
February 15, 2022
Freeze & Thaw
What do you need for scalable freezing of biopharmaceuticals in single-use bags?
Check out our Scalability Guide.
Michael Eder
August 9, 2021
Freeze & Thaw
In order to preserve biopharmaceutical properties, bulk drug substances are commonly frozen before they are being stored or sent on their way around the globe. Read more about the players and their innovations!
Michael Eder
June 29, 2021
Freeze & Thaw
How x-ray views from frozen single use bags affirm plate-based freezers as spearheaded freezing technology in Biopharma
Johannes Kirchmair
May 12, 2021
Freeze & Thaw
In this publication we show that the intital price can be deceiving and there are significant additional costs during ongoing usage in the long term. Plate freezers ensure a complete, consistent, and fast freezing (and thawing) to ensure the quality of your high-valued drug substance is maintained, and through simple lifecylcle analysis they outpace conventional options regarding total costs.
Alexander Fuchs
January 19, 2021
Freeze & Thaw
The Single Use Bag has many advantages in the manufacturing and development process of biopharmaceutical products. Find out what these advantages are in this blog post!
Michael Eder
February 10, 2020
Articles by Biopharmaceutical Products:
Articles by Manufacturing Processes:
E-Book
In this publication we show that the initial price can be deceiving and there are significant additional costs during ongoing usage in the long term. Plate freezers ensure a complete, consistent, and fast freezing (and thawing) to ensure the quality of your high-valued drug substance is maintained, and through simple lifecycle analysis they outpace conventional options regarding total costs.
E-Book
Scalability around freezing means the ability to guarantee constant freezing kinetics on proteins (biopharmaceutical molecules) in all scales, filling volumes and loading scenarios. This guide covers how to achieve scalable freezing & thawing of biopharmaceuticals by showing What is scalability? Setup for controlled icefront growth speed Scalability results Outcomes
E-Book
The study was conducted aiming to optimize the cryogenic freezing process of the mammalian CHO-K1 cell line with an innovative controlled rate liquid nitrogen freezer (RoSS.LN2F). The study incorporated three viability assays to comprehensively assess the impact of varying freezing rates on post-thaw cell recovery | Trypan blue | LIVE/DEAD | Fluorescence.
