Cell & Gene therapy

October 11, 2022

Viral vectors for gene therapy: What to expect in 2023

mike-marciniak
Mike Marciniak

Viral vectors are looking ahead a bright future in gene therapies. In this article, we give you an overview of the most frequently used viral vectors and have a glimpse at their possible future applications.

October 10, 2022

Small batch manufacturing & fill-finish in cell and gene therapy

michael-muehlegger
Michael Mühlegger

A great example is the treatment of insidious cancers with CAR T-cells, that relies on modifying the patient’s own T-cells to instill them with a targeted way to fight cancer cells. Learn more why forming strong collaborations will solve many issues!

July 4, 2022

AAV production workflow – where do we come in?

mike-marciniak
Mike Marciniak

The production of AAVs requires to fulfill high standards and is thus in need of state of the art technologies. Find out what the key elements in the production of AAVs are and how our products help to carry them out.

July 4, 2022

Safe handling of AAVs

mike-marciniak
Mike Marciniak

Adeno-associated viruses are an increasingly important tool in biopharma, used for example as vectors for gene therapy and vaccines. But how are they adequately – and safely – handled? Here are some key aspects to consider along their supply chain.

June 23, 2022

CAR-T manufacturing process and the supply chain behind it

micheal-eder
Michael Eder

Mastering the complex CAR T manufacturing process and the associated supply chain challenges in the cell and gene area are the major bottlenecks during the large-scale commercialization of highly promising CAR T cell products. 


 

June 9, 2022

Gene therapy manufacturing - 5 requirements to scale up

michael-muehlegger
Michael Mühlegger

Gene therapies have become a highly promising field of groundbreaking next generation treatment, but there are some challenges to face within the manufacturing process. Here are 5 factors that will be crucial for upscaling gene therapy manufacturing with single-use technology.

March 28, 2022

Costs for CAR T-cell therapy - How to deploy cost-efficiency

michael-muehlegger
Michael Mühlegger

CAR T-cell treatments are deservedly on the rise, as the effectiveness of CAR T-cell products for formerly hard to treat hematology malignancies has been established in clinical trials. This article will highlight one of the less discussed issues of immunotherapy in cancer treatment: it’s current price tag could hamper the broad accessibility to patients.

February 15, 2022

Whitepaper: How controlled freezing enables scalability

micheal-eder
Michael Eder

In a comprehensive study the impact of ice front growth speed on scalability of freezing protein solutions has been evaluated.

January 10, 2022

Safety & Speed: handling two major factors in CAR T-cell therapy

micheal-eder
Michael Eder

In order to allow for a smooth and functioning process, a reliable supply chain, tailored to the specific needs of autologous therapies, is a prerequisite. Single Use Support has developed an end-to-end process solution for cell and gene therapies.

December 22, 2021

Logistic solutions for CAR T-cell therapy - let's scale!

micheal-eder
Michael Eder

Single Use Support develops scalable solutions and optimizes processes for protecting, fill & freeze, shockfreezing, packaging and handling of small volume cell and gene therapeutics. Learn more about logistics for CAR T-cell therapy!

December 20, 2021

Supply chain optimization in cell and gene therapies

barbara-m-fischer
Barbara M. Fischer

Single Use Support is solving problems related to supply chain management through the development of smart packaging and related smart technologies for CAR T-cell therapy. Read more!

December 20, 2021

Advanced therapy medicinal products - a new era of medicine

micheal-eder
Michael Eder

Advanced therapy medicinal products (ATMPs) are medicines for human use that are based on genes, tissues or cells. Accordingly, they can be classified into three main types, namely gene therapy, tissue engineered- and somatic-cell therapy medicines. Read more!