All articles about Vaccines

Vaccines

Thawing drug substance: best practices

For drug substances that undergo a freezing process during manufacturing, thawing at some point is only a logical consequence. However, there are several factors to be considered for this seemingly easy procedure – find out more in this article!

micheal-eder

Michael Eder

March 8, 2023

Vaccines

Freezing drug substance – taking control over large volume pharmaceutical freezing

Freezing large volumes of drug substance can be a challenging endeavor. In this article, we will discuss main considerations as well as possible solutions for this delicate process.

Alexander Fuchs | Single Use Support

Alexander Fuchs

March 7, 2023

Vaccines

Loss of drug substance - the challenges and chances of product loss

In recent years, if not decades, gene therapies have proven to be key drivers of growth in the pharmaceutical industry. Learn more how SUSupport takes on the chances in loss of drug substances.

Claus Exenberger - Single Use Support

Claus Exenberger

August 24, 2021

Vaccines

Frozen Storage and Shipping in biopharma with RoSS

Single Use Suppport’s RoSS (robust storage and shipping) shell, composed of an outer sleeve of robust stainless-steel and an adaptive inner layer of 3D foam, contributes to a safe journey. It warrants the single-use bag’s intact arrival at its final destination, keeping its precious contents protected from biocontamination and other damages. 

Claus Exenberger - Single Use Support

Claus Exenberger

May 20, 2021

Discover more topics

Articles by Biopharmaceutical Products:

Recommended Downloads

E-Book

eBook: Filling Gaps in Managing Large Volumes of Biologics

Aseptic aliquotation and cryopreservation of drug substances are crucial process steps in bioprocessing. Even though they’re not in the spotlight of biomanufacturing. In drug development and drug delivery, biologics must be transferred at numerous occasions. Along the journey of monoclonal antibodies, vaccines and more, the drug substance passes lots of process steps where liquid transfer is required. This is relevant for the transitions between upstream processing, downstream processing and fill & finish, but also within these manufacturing milestones. The market of fluid & cold chain management has great growth potential and is on its way to professionalization and industrialization. To meet the challenges of manufacturing drug substances, Single Use Support helps manufacturers and CDMOs to advance their fluid & cold chain management process to achieve a secure and efficient process for liquids on the basis of single-use bags.

E-Book

Whitepaper: Scalable Freezing & Thawing of Pharmaceutical Bulk

The process of freezing can lead to a denaturation of the protein. In fact, parts of the protein solution will always show less activity based on the stress the protein is exposed to during freezing and thawing. It is therefore important to optimize the freezing and thawing process in order to minimize activity loss. A key parameter for this process is the freezing or thawing rate.

E-Book

Whitepaper: Automated Aseptic Filling

Read our Whitepaper about Automated Aseptic Filling in Pharmaceutical Manufacturing | Discover why automatic filling solutions are preferable to manual filling.