Cell & Gene therapy

In a recent study, freezing protocols were tested with the RoSS.LN2F controlled liquid nitrogen freezer to find the optimal freezing rate for CHO-K1 cells in order to achieve maximum cell viability. 

The objective of an optimal cryopreservation strategy is to deactivate (put on hold) degenerative cellular pathways and preserve proliferative potential by reducing the temperature below –130°C. To reduce the effects of ice crystal and osmotic injuries, cryopreservation protocols usually incorporate cryoprotective agents (CPAs).

Adequate quality control samples retained before cell therapy treatment are a crucial component of effective regulation and need to represent the conditions and history in the cryobag. A deep dive into GMP Annex 1 on ATMP Cryopreservation.

Considering the widespread need for efficient pDNA production, the industry is seeking to improve the current manufacturing process. In this article, we will discover how single-use technologies can contribute to pDNA manufacturing optimizations.

In this article, we will give an overview of the pDNA manufacturing market – not only taking a look at the dry figures, but also highlighting the services that are offered by important plasmid DNA manufacturing companies.

Plasmid DNA fulfills several functions in bacteria, but they are also widely used in the biopharma sector. In this article, we will uncover their key functions.

The pDNA manufacturing process is multifaceted yet essential in the biopharmaceutical industry. Here, we will describe the process step by step.

Plasmids are part of the genetic material in bacteria, complementing chromosomal DNA with additional functions. But there is much more to plasmids, as you can read in this article.

Plasmid DNA is not only found in bacteria, but also ubiquitous in biotechnology. In this article, we have collected 7 interesting facts on pDNA.

Single Use Support unveils its latest customized innovation within the product range of automated of biopharmaceutical manufacturing, RoSS.FILL. With its unmatched precision and cutting-edge technology, RoSS.FILL CGT is a game-changer for the cell and gene therapy industry.

The term "autologous" is most frequently found in the context of cell therapy. In this article, we will therefore take a closer look at this revolutionary therapeutic approach.

What does "allogeneic" mean, precisely? How do allogeneic cell therapies work, and what is the difference to autologous approaches? Questions like these will be answered in this article.