Bioprocessing
Proper storage of cells and maintenance of a cell bank is essential to uphold the integrity and reproducibility of experimental results. In this article, we will show best practices for maintaining a cell bank, from initial cell line characterization to cGMP compliance, storage, and troubleshooting tips.
Michael Eder
August 1, 2023
Bioprocessing
By preserving and storing valuable cell lines, cell banking ensures a stable and consistent source of cells for various applications. In this blog post, we will explore the numerous advantages of cell banking and its pivotal role in driving advancements in the fields of science and medicine.
Michael Eder
August 1, 2023
Bioprocessing
At the core of cutting-edge research and biopharmaceutical production lies the crucial need to preserve and store precious cell lines, ensuring their availability for future studies and therapeutic applications. In this article, we will explore the purpose and applications of cell banking, examining its significance in scientific discoveries and medical breakthroughs.
Michael Eder
August 1, 2023
Bioprocessing
Cell banking plays a key role in securing valuable cell lines and biological resources for future research and applications in the field of biotechnology. This article aims to provide a comprehensive overview of cell banking, its definition, importance, and the essential components involved in establishing and maintaining cell banks.
Michael Eder
August 1, 2023
Bioprocessing
A fundamental process to preserve the ex vivo viability of cells is freezing them to extremely low temperatures. This is a complex and delicate task, requiring both expertise and professional equipment. In this article, we will take a look at the most important aspects of the cell freezing process.
Brian Moloney
August 1, 2023
Bioprocessing
Automation is affecting various aspects of our lives, including bioprocessing. In this article, we will explore the advantages that come with this development.
Michael Mühlegger
April 12, 2023
Bioprocessing
Spray drying often leads to product losses of mAbs or vaccines of more than 30%. Plate-based freezing and thawing solutions enable controlled handling of bulk intermediates safely in a vendor-independent, modular and scalable fluid and cold chain management process.
Daniel Tischler
April 12, 2023
Bioprocessing
Bioprocessing is a fundamental technology for various aspects of our lives, including the biopharma industry. In this article, we will provide some interesting facts about applications, techniques and future expectations regarding bioprocessing.
Khalil Essani
April 6, 2023
Bioprocessing
The following article aims to take a closer look at the term “bulk drug substance” and its meaning, as well as to investigate smart solutions to shorten the phase between development and blockbuster production. Read more about the solution for the biopharmaceutical industry!
Michael Eder
March 22, 2023
Bioprocessing
Microbial fermentation is a powerful, flexible microbiology process used to generate microbial cells or biomass such as proteins and enzymes for the production of vaccines and therapeutics. There are still some challenges to overcome. Many of these challenges in fermentation manufacturing can be solved by replacing traditional systems with single-use technologies.
Daniel Tischler
March 17, 2023
Bioprocessing
Microbial fermentation manufacturing is an effective method for the production of APIs, bioconjugates and smaller biologicals that play an important role in biotechnology and the production of biopharmaceuticals. Manufacturers face different challenges during microbial fermentation. Explore the 7 biggest challenges, followed by the introduction of new solutions.
Daniel Tischler
March 16, 2023
Bioprocessing
The filling and freezing of large volumes for fermentation is an essential part during different production steps in upstream and downstream processing. In the following, we will explain why it is important to act fast and how an optimization of the process can be achieved.
Daniel Tischler
March 16, 2023
Articles by Biopharmaceutical Products:
Articles by Manufacturing Processes:
E-Book
Cell Banking in Seed Train Intensification is a crucial process step in upstream bioprocessing for biopharmaceutical production. Cells that can be cultured into large aliquots, e.g. with cell suspensions, can greatly optimize the cell culture intensification process.
E-Book
Guide about Handling Liquids in Biopharmaceutical Fermentation | Scalability in Microbial Mammalian Fungal Fermentation | Replacing Spray Drying and Lyophilization with Bulk Plate Freezing | Speed of Handling Large Volumes in Fermentation | Bag Breakages in fermentation cold chain logistics
E-Book
Throughout the entire manufacturing process, pharmaceutical liquids are transferred and have touchpoints within upstream bioprocessing, downstream bioprocessing and fill/finish. Single Use Support provides single-use assemblies and with it capabilities in Dual Sourcing, Customization and Qualification. | Strengthening the Supply Chain | Development of off-the-shelf assemblies | GMP-compliant solutions
