All articles

Bioprocessing

Single-use bioprocessing: Why it pays off to switch to single-use systems now

Single-use systems are looking ahead a bright future – but what is it that manufacturers need to consider before the switch? Learn more about it in this article!

1640281789974

David Seifert

September 15, 2022

Single-use Technology

Case Study - Reducing Product Loss | Process-independence

Optimize process operations and save both, CAPEX and OPEX, when you plan to expand product capacities for biopharmaceutical manufacturing - especially for greenfield facilities. Read how you gain process-independence which in turn increases (cost-)efficiency in manufacturing processes.

Claus Exenberger - Single Use Support

Claus Exenberger

August 22, 2022

Bioprocessing

Simplifying Cryopreservation of Cell Monolayers

Advanced cell-based assay workflow with CryoLogyx Thaw and Test pre-plated cell and controlled, scalable freezing process solution RoSS.pFTU to achieve effective cryopreservation of cells.

BRMO

Brian Moloney

August 9, 2022

Bioprocessing

Cryogenic Freezing: All you need to know

Cryopreservation is an effective procedure for the quality-preserving storage of many biomaterials. Find out what cryopreservation actually is, what has to be considered along the process and where it is applied – all summed up in this article.

daniel-tischler

Daniel Tischler

August 1, 2022

Single-use Technology

Case Study: Reducing product loss | Hybrid for primary packaging

Harmonize the process for different types of single-use primary packaging. Protective shell solutions and hybrid systems optimize liquid transfer in Biopharma. 

Claus Exenberger - Single Use Support

Claus Exenberger

July 28, 2022

Freeze & Thaw

Pharmaceutical cold storage – overview of all freezing ranges

Temperature plays a significant role in the production and distribution of several revolutionary biologics. But how does the pharmaceutical cold chain work, and what temperature ranges are most frequently chosen? You will find out in this article!

Alexander Fuchs | Single Use Support

Alexander Fuchs

July 25, 2022

Freeze & Thaw

Ultra-cold freezing and storing – considerations & solutions

Implementing cold freezing and storing in supply chains is oftentimes inevitable when dealing with certain biopharmaceuticals. Learn what the main considerations are and find out how to face related challenges.

daniel-tischler

Daniel Tischler

July 19, 2022

Cell & Gene Therapy

CAR-T manufacturing: process and supply chain strategies

Mastering the complex CAR T manufacturing process and the associated supply chain challenges in the cell and gene area are the major bottlenecks during the large-scale commercialization of highly promising CAR T cell products. 


 

micheal-eder

Michael Eder

June 23, 2022

Single-use Technology

Case Study: Reducing product loss | Bag-independence

Learn about the benefits of supplier-agnostic solutions around single-use bioprocess containers that help minimize product loss.

Claus Exenberger - Single Use Support

Claus Exenberger

June 20, 2022

Nucleic Acids

mRNA vaccines: How to safely ship and store them

mRNA vaccines require high diligency along their supply chain. This is why every step in the mRNA vaccine supply chain must be carefully planned, carried out in a safe and controlled manner and requires appropriate, innovative technologies.

daniel-tischler

Daniel Tischler

June 9, 2022

Cell & Gene Therapy

Gene therapy manufacturing - 5 requirements to scale up

Gene therapies have become a highly promising field of groundbreaking next generation treatment, but there are some challenges to face within the manufacturing process. Here are 5 factors that will be crucial for upscaling gene therapy manufacturing with single-use technology.

michael-muehlegger

Michael Mühlegger

June 9, 2022

Single-use Technology

Case Study: Reducing product loss | Cost-efficiency

It is the key issue in the management of bulk medicines: How can product loss be avoided or at least reduced? This article explains everything about this topic!

Claus Exenberger - Single Use Support

Claus Exenberger

June 8, 2022

Recommended Downloads

E-Book

eBook: Filling Gaps in Managing Large Volumes of Biologics

Aseptic aliquotation and cryopreservation of drug substances are crucial process steps in bioprocessing. Even though they’re not in the spotlight of biomanufacturing. In drug development and drug delivery, biologics must be transferred at numerous occasions. Along the journey of monoclonal antibodies, vaccines and more, the drug substance passes lots of process steps where liquid transfer is required. This is relevant for the transitions between upstream processing, downstream processing and fill & finish, but also within these manufacturing milestones. The market of fluid & cold chain management has great growth potential and is on its way to professionalization and industrialization. To meet the challenges of manufacturing drug substances, Single Use Support helps manufacturers and CDMOs to advance their fluid & cold chain management process to achieve a secure and efficient process for liquids on the basis of single-use bags.

E-Book

Whitepaper: How Controlled & Scalable Freezing Becomes Reality

Scalability around freezing means the ability to guarantee constant freezing kinetics on proteins (biopharmaceutical molecules) in all scales, filling volumes and loading scenarios. This guide covers how to achieve scalable freezing & thawing of biopharmaceuticals by showing What is scalability? Setup for controlled icefront growth speed Scalability results Outcomes

E-Book

Whitepaper: Automated Aseptic Filling

Read our Whitepaper about Automated Aseptic Filling in Pharmaceutical Manufacturing | Discover why automatic filling solutions are preferable to manual filling.