Knowledge

September 13, 2023

What is the function of plasmid DNA?

michael-muehlegger
Michael Mühlegger

Plasmid DNA fulfills several functions in bacteria, but they are also widely used in the biopharma sector. In this article, we will uncover their key functions.

September 12, 2023

Plasmid DNA manufacturing: The process simply explained

michael-muehlegger
Michael Mühlegger

The pDNA manufacturing process is multifaceted yet essential in the biopharmaceutical industry. Here, we will describe the process step by step.

September 7, 2023

What is a plasmid?

michael-muehlegger
Michael Mühlegger

Plasmids are part of the genetic material in bacteria, complementing chromosomal DNA with additional functions. But there is much more to plasmids, as you can read in this article.

September 7, 2023

Plasmid DNA – 7 facts about pDNA

michael-muehlegger
Michael Mühlegger

Plasmid DNA is not only found in bacteria, but also ubiquitous in biotechnology. In this article, we have collected 7 interesting facts on pDNA.

September 6, 2023

Sustainable Freezing in Biopharma: An Exploration of Natural Gas Usage

Alexander Fuchs | Single Use Support
Alexander Fuchs

In the biopharmaceutical sector, the utilization of F-Gases is on a decline. However, the need for cryopreservation of drug substances will remain. In order to contribute to a more environmentally friendly freezing of drugs, more sustainable technologies need to be developed and applied. But is sustainable freezing even possible?

August 22, 2023

Revolutionizing Commercial Aliquotation in Advanced Therapies

BRMO
Brian Moloney

Single Use Support unveils its latest customized innovation within the product range of automated of biopharmaceutical manufacturing, RoSS.FILL. With its unmatched precision and cutting-edge technology, RoSS.FILL CGT is a game-changer for the cell and gene therapy industry.

August 11, 2023

Cryopreservation techniques & best practice freezing methods

BRMO
Brian Moloney

The preservation of cells at cryogenic temperature can be achieved using different techniques. This is far from a simple freezing process; it's a carefully controlled method that prevents the formation of ice crystals, thus maintaining the integrity of the biological material.

August 11, 2023

How to prepare cells for cryopreservation?

BRMO
Brian Moloney

This guide provides an overview of the necessary steps and considerations for preparing cells for cryopreservation. Key topics include selecting appropriate cells, cultivating and harvesting them under controlled conditions, utilizing proper cryoprotective agents, and applying specific freezing techniques.

August 10, 2023

Cell viability & viability assays: 7 facts to be aware of

BRMO
Brian Moloney

In research, medicine and biotechnology, cell viability is an elementary parameter and Critical Quality Attribute (CQA). In this article, we will present you 7 facts regarding the term, related concepts, improvement possibilities and more.

August 10, 2023

Cryopreservation: Purpose, process & applications

BRMO
Brian Moloney

Cryopreservation is essential to maintain ex vivo viability of organic materials – indispensable, for instance, in fields like cell banking. In this article, we will explore central aspects of this technique.

August 9, 2023

cGMP cell banking: Aliquoting & controlled freezing of cells in less than 1 hour

BRMO
Brian Moloney

As the market is constantly evolving, new, fully automated solutions are offered to make GMP cell banking and cGMP cell banking easier to achieve. Single Use Support’s solutions do not only reach out to help make the handling of cell banks safer and more efficient, but also help to support smaller-scale projects through scalable solutions. 

August 9, 2023

Thawing cells – process, difficulties & recommendations

BRMO
Brian Moloney

Cell thawing is a critical procedure in the area of life science and medicine. Ensuring a gentle thawing of frozen cells is essential for preserving their viability and functionality. In this article, we will highlight the cell thawing process, discuss common challenges, and provide recommendations for achieving optimal results in cell banking.