Knowledge

September 19, 2023

What is the difference between adeno-associated virus and adenovirus?

michael-muehlegger
Michael Mühlegger

The main difference between adeno-associated viral vectors (AAV) and adenoviral vectors (AVV) is their genetic makeup. AAV is composed of a single-stranded DNA viral vector, while adenoviral vectors consist of double-stranded DNA.

September 19, 2023

Types of viral vectors

michael-muehlegger
Michael Mühlegger

Various types of viral vectors are central to genetic research and medical advancements. These small carriers, obtained from various viruses, play an essential role in gene therapy and beyond. In this exploration, we will examine different types, the applications, unique attributes, and the complex terrain of producing viral vectors.

September 18, 2023

Adeno-Associated Virus (AAV) for gene therapy

Khalil Essani - Single Use Support
Khalil Essani

The adeno-associated virus (AAV) is a very popular viral vector with great potential available for gene delivery. This article explores AAV vectors, their role in gene therapy, and their associated advantages and disadvantages.

September 13, 2023

Plasmid DNA manufacturing companies – market overview

daniel-tischler
Daniel Tischler

In this article, we will give an overview of the pDNA manufacturing market – not only taking a look at the dry figures, but also highlighting the services that are offered by important plasmid DNA manufacturing companies.

September 13, 2023

What is the function of plasmid DNA?

michael-muehlegger
Michael Mühlegger

Plasmid DNA fulfills several functions in bacteria, but they are also widely used in the biopharma sector. In this article, we will uncover their key functions.

September 12, 2023

Plasmid DNA manufacturing: The process simply explained

michael-muehlegger
Michael Mühlegger

The pDNA manufacturing process is multifaceted yet essential in the biopharmaceutical industry. Here, we will describe the process step by step.

September 7, 2023

What is a plasmid?

michael-muehlegger
Michael Mühlegger

Plasmids are part of the genetic material in bacteria, complementing chromosomal DNA with additional functions. But there is much more to plasmids, as you can read in this article.

September 7, 2023

Plasmid DNA – 7 facts about pDNA

michael-muehlegger
Michael Mühlegger

Plasmid DNA is not only found in bacteria, but also ubiquitous in biotechnology. In this article, we have collected 7 interesting facts on pDNA.

September 6, 2023

Sustainable Freezing in Biopharma: An Exploration of Natural Gas Usage

Alexander Fuchs | Single Use Support
Alexander Fuchs

In the biopharmaceutical sector, the utilization of F-Gases is on a decline. However, the need for cryopreservation of drug substances will remain. In order to contribute to a more environmentally friendly freezing of drugs, more sustainable technologies need to be developed and applied. But is sustainable freezing even possible?

August 22, 2023

Revolutionizing Commercial Aliquotation in Advanced Therapies

BRMO
Brian Moloney

Single Use Support unveils its latest customized innovation within the product range of automated of biopharmaceutical manufacturing, RoSS.FILL. With its unmatched precision and cutting-edge technology, RoSS.FILL CGT is a game-changer for the cell and gene therapy industry.

August 11, 2023

Cryopreservation techniques & best practice freezing methods

BRMO
Brian Moloney

The preservation of cells at cryogenic temperature can be achieved using different techniques. This is far from a simple freezing process; it's a carefully controlled method that prevents the formation of ice crystals, thus maintaining the integrity of the biological material.

August 11, 2023

How to prepare cells for cryopreservation?

BRMO
Brian Moloney

This guide provides an overview of the necessary steps and considerations for preparing cells for cryopreservation. Key topics include selecting appropriate cells, cultivating and harvesting them under controlled conditions, utilizing proper cryoprotective agents, and applying specific freezing techniques.