December 19, 2022

What is upstream and downstream processing?

Bernhard Schlichtner

Upstream and downstream processing are two steps inherent to the production of active pharmaceutical ingredients (API) used in biopharmaceuticals. The production is challenged by increasing regulation and manufacturing costs. This calls for flexible solutions, which is why a growing number of manufacturing processes utilize single-use systems

November 8, 2022

Controlling cryogenic freezing with liquid nitrogen

Daniel Tischler

To control cryogenic freezing is not an easy task, especially when liquid nitrogen is involved. To keep small molecules chemically stable and prevent chemical degradation, the right practices have to be in place. Find out everything about controlled cryogenic freezing with LN2 in this article!

November 8, 2022

What are Antibody-Drug Conjugates (ADCs)?

Bernhard Schlichtner

Antibody-Drug Conjugates are rather novel and exciting biopharmaceutical agents. This article will give you an overview of what is to know about ADCs – find out more!

November 7, 2022

Antibody-Drug Conjugate Companies: Who is working on the ADC market?

Bernhard Schlichtner

The antibody-drug conjugates (ADCs) market is expected to grow significantly in the next few years. But what are the key players in this competitive landscape? Find out more in this article!

November 5, 2022

Process safety in fluid management of ADCs

Mike Marciniak

When handling ADCs, there are several challenges to overcome, including process safety in their fluid management. Read about these difficulties and how to overcome them in this article!

October 13, 2022

Controlled freezing of ADCs

Johannes Kirchmair

Antibody-drug conjugates might revolutionize the treatment of cancer and various other diseases. However, there are some challenges to overcome in their handling, including controlled freezing – find out more in this article!

October 12, 2022

Mission completed – and now? How RoSS® Shell is to be recycled

Michael Eder

Once they have fulfilled their purpose to protect valuable biologics, the question for our RoSS containers arises: What now? This is why we summarized information on the recycling of our containers for single use bags in this article.

October 11, 2022

Viral vectors for gene therapy: What to expect in 2023

Mike Marciniak

Viral vectors are looking ahead a bright future in gene therapies. In this article, we give you an overview of the most frequently used viral vectors and have a glimpse at their possible future applications.

October 10, 2022

Small batch manufacturing & fill-finish in cell and gene therapy

Michael Mühlegger

A great example is the treatment of insidious cancers with CAR T-cells, that relies on modifying the patient’s own T-cells to instill them with a targeted way to fight cancer cells. Learn more why forming strong collaborations will solve many issues!

September 15, 2022

Single-use bioprocessing: Why it pays off to switch to single-use systems now

Mike Marciniak

Single-use systems are looking ahead a bright future – but what is it that manufacturers need to consider before the switch? Learn more about it in this article!

August 9, 2022

Simplifying Cryopreservation of Cell Monolayers

Brian Moloney

Advanced cell-based assay workflow with CryoLogyx Thaw and Test pre-plated cell and controlled, scalable freezing process solution RoSS.pFTU to achieve effective cryopreservation of cells.

August 1, 2022

Cryogenic freezing process in biopharma

Daniel Tischler

Cryopreservation is an effective procedure for the quality-preserving storage of many biomaterials. Find out what cryopreservation actually is, what has to be considered along the process and where it is applied – all summed up in this article.