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Vaccines

An introduction to biosimilars

Biosimilars are a popular alternative to reference biologics they resemble. But what has led to this popularity, and what’s to know about their manufacturing? Find out in this article!

Michael Eder

May 8, 2024

Vaccines

Biologics: An introduction to biologic drugs

In the past few decades, biologics have become an integral pillar in healthcare worldwide. Deriving from living organisms, they hold huge therapeutic potential, with many possible applications still undiscovered. In this article, we will give you an overview of this exciting class of pharmaceuticals.

Michael Eder

May 8, 2024

Vaccines

Safe storage of biologics: Requirements & solutions

Once biologics are produced, they need to be stored for shorter or longer periods of time, with dedicated storage requirements to be met. Here, we will uncover these requirements, along with solutions to fulfill them.

Alexander Fuchs

May 8, 2024

FDA approved antibody-drug conjugates for cancer therapy

Bioconjugates

FDA approved Antibody Drug Conjugates (ADCs)

ADCs offer new, highly promising approaches in the therapy of various cancer types, and the number of approved ADCs is continuously growing. In this article, we will have a look at ADCs currently approved.

Michael Mühlegger

May 7, 2024

Biologics vs. Biosimilars – what’s the difference?

Vaccines

Biologics vs. Biosimilars: What is the difference?

Biologics and biosimilars are both innovative and frequently used therapeutics, but where do they differ? They will be uncovered in this article.

Michael Eder

May 6, 2024

Vaccines

Freezing biologics – best practices

There is more than one way to prepare biologics for long-term storage under temperature-controlled conditions – in this article, we will explore some of the main freezing methods.

Alexander Fuchs

May 6, 2024

Bioconjugates

ADC manufacturing: Process, Challenges & Solutions

Scale-up and industrial production of ADCs face complications due to the high safety measures which need to be taken to guarantee product efficacy and a protected working environment for staff and manufacturers. In this article we seek out to give you an overview of the different challenges during ADC manufacturing while also introducing solutions which help to ensure aseptic production methods through single-use-technologies and end-to-end systems.

Brian Moloney

May 5, 2024

End-to-end Solution

An introduction to therapeutic proteins

Therapeutic proteins hold promise in the treatment of numerous medical conditions, and progress in this field is far from being over. This is reason enough to take a general look at this class of therapeutics.

Alexander Fuchs

April 10, 2024

End-to-end Solution

Protein storage: How to increase protein stability?

Prior to be used in diagnostics or therapeutics, proteins have to be safely stored. In this article, we will assess methods to preserve their stability upon storage.

Alexander Fuchs

April 10, 2024

Optimizing pDNA production using advanced single-use technologies

End-to-end Solution

Protein production and optimization strategies

Protein production is a crucial process that which a large variety of pharmaceutical products rely on. Therefore, we will discuss this procedure in this article, along with possibilities to improve it.

Khalil Essani

April 9, 2024

End-to-end Solution

Protein stability – all you need to know

Protein stability is crucial to be maintained along the manufacturing process of protein-based products. In this article, we will discover what influences protein stability, along with methods to assess and increase it.

Khalil Essani

April 9, 2024

Loss of drug substance - the challenges and chances

Vaccines

What are Active Pharmaceutical Ingredients (APIs)?

Active Pharmaceutical Ingredients (APIs) are the cornerstone of pharmaceutical drugs, serving as the primary agents responsible for delivering therapeutic effects to patients.

Michael Eder

March 21, 2024

Recommended Downloads

E-Book

eBook: Filling Gaps in Managing Large Volumes of Biologics

Aseptic aliquotation and cryopreservation of drug substances are crucial process steps in bioprocessing. Even though they’re not in the spotlight of biomanufacturing. In drug development and drug delivery, biologics must be transferred at numerous occasions. Along the journey of monoclonal antibodies, vaccines and more, the drug substance passes lots of process steps where liquid transfer is required. This is relevant for the transitions between upstream processing, downstream processing and fill & finish, but also within these manufacturing milestones. The market of fluid & cold chain management has great growth potential and is on its way to professionalization and industrialization. To meet the challenges of manufacturing drug substances, Single Use Support helps manufacturers and CDMOs to advance their fluid & cold chain management process to achieve a secure and efficient process for liquids on the basis of single-use bags.

Whitepaper_Controlled_Scalable_Freezing_SEP22

E-Book

Whitepaper: How Controlled & Scalable Freezing Becomes Reality

Scalability around freezing means the ability to guarantee constant freezing kinetics on proteins (biopharmaceutical molecules) in all scales, filling volumes and loading scenarios. This guide covers how to achieve scalable freezing & thawing of biopharmaceuticals by showing What is scalability? Setup for controlled icefront growth speed Scalability results Outcomes

1021-Whitepaper_RoSS.FILL_Automated Aseptic Filling_Single Use Support

E-Book

Whitepaper: Automated Aseptic Filling

Automated Aseptic Filling Unprecedented flexibility to filling well