Knowledge

August 10, 2023

Cell viability & viability assays: 7 facts to be aware of

BRMO
Brian Moloney

In research, medicine and biotechnology, cell viability is an elementary parameter and Critical Quality Attribute (CQA). In this article, we will present you 7 facts regarding the term, related concepts, improvement possibilities and more.

August 10, 2023

Cryopreservation: Purpose, process & applications

BRMO
Brian Moloney

Cryopreservation is essential to maintain ex vivo viability of organic materials – indispensable, for instance, in fields like cell banking. In this article, we will explore central aspects of this technique.

August 9, 2023

cGMP cell banking: Aliquoting & controlled freezing of cells in less than 1 hour

BRMO
Brian Moloney

As the market is constantly evolving, new, fully automated solutions are offered to make GMP cell banking and cGMP cell banking easier to achieve. Single Use Support’s solutions do not only reach out to help make the handling of cell banks safer and more efficient, but also help to support smaller-scale projects through scalable solutions. 

August 9, 2023

Thawing cells – process, difficulties & recommendations

BRMO
Brian Moloney

Cell thawing is a critical procedure in the area of life science and medicine. Ensuring a gentle thawing of frozen cells is essential for preserving their viability and functionality. In this article, we will highlight the cell thawing process, discuss common challenges, and provide recommendations for achieving optimal results in cell banking. 

August 9, 2023

Homogenization of cells & aliquotation in single-use bags

BRMO
Brian Moloney

Who can relate to the situation when every cell aliquot is different? That's why cell homogenization and aliquotation are important requirements in modern cell biology research, relevant for scientists and laboratory staff. Scientists and process engineers benefit from uniform cell distribution throughout multiple single-use bioprocess containers for cell banking or other bioprocessing steps.

August 3, 2023

Types of cell banks: An overview

micheal-eder
Michael Eder

In cell banking, one can distinguish four different types of cell banks, all of which are involved in the manufacturing of cell-based products. In this article, we will discuss them all.

August 3, 2023

Cell bank manufacturing: From master to working cell bank

BRMO
Brian Moloney

Cell banks are fundamental in the production of several biopharmaceutical products, their manufacturing a highly complex process. In this article, we will explain cell bank manufacturing in detail, including the challenges it is related to.

August 2, 2023

The differences between master cell bank (MCB) and working cell bank (WCB)

micheal-eder
Michael Eder

Both master and working cell banks belong to the four general types of cell banks. Although having much in common, there are some major differences between MCBs and WCBs, which we will uncover in this article.

August 2, 2023

Cryopreservation of cells: Preserving cells for future use

BRMO
Brian Moloney

Cryopreservation is a necessary procedure to maintain cell viability during ex vivo storage. In this article, we will provide some general information on cell cryopreservation, but also discuss different tools, challenges and an exemplary protocol.

August 1, 2023

How to maintain a cell bank?

micheal-eder
Michael Eder

Proper storage of cells and maintenance of a cell bank is essential to uphold the integrity and reproducibility of experimental results. In this article, we will show best practices for maintaining a cell bank, from initial cell line characterization to cGMP compliance, storage, and troubleshooting tips.

August 1, 2023

Advantages of cell banking

micheal-eder
Michael Eder

By preserving and storing valuable cell lines, cell banking ensures a stable and consistent source of cells for various applications. In this blog post, we will explore the numerous advantages of cell banking and its pivotal role in driving advancements in the fields of science and medicine.

August 1, 2023

The purpose of cell banking: Uses & Applications

micheal-eder
Michael Eder

At the core of cutting-edge research and biopharmaceutical production lies the crucial need to preserve and store precious cell lines, ensuring their availability for future studies and therapeutic applications. In this article, we will explore the purpose and applications of cell banking, examining its significance in scientific discoveries and medical breakthroughs.