All articles

Bioprocessing

Inline buffer dilution: an agile system for downstream processes

Inline buffer dilution (IBD) is a method for on demand buffer preparation from buffer concentrates at the point of use. This article will give an overview of the inline buffer dilution process and discuss its benefits over the traditional formulation of buffer solutions.

BRMO

Brian Moloney

February 2, 2022

Biopharma

At the forefront of Pharma 4.0

There is no full Pharma 4.0 manufacturing in place yet, but there are first innovations to build on.
Currently numerous manual handling steps in biopharmaceutical manufacturing come along with a high degree of failures in manufacturing facilities deriving from human errors in operative handling. 

micheal-eder

Michael Eder

January 20, 2022

Cell & Gene Therapy

Safety & Speed: handling two major factors in CAR T-cell therapy

In order to allow for a smooth and functioning process, a reliable supply chain, tailored to the specific needs of autologous therapies, is a prerequisite. Single Use Support has developed an end-to-end process solution for cell and gene therapies.

micheal-eder

Michael Eder

January 10, 2022

Fill & Filtration

How to safely connect a single-use tubing set?

When safety, time and flexibility are of the essence, the solution should be an easy one. This is why the team at MyManifold have come up with an intuitive, easy-to-use configurator for sterile filling systems. Users can design their own assembly prototype. Read how!

BRMO

Brian Moloney

January 3, 2022

Fill & Filtration

Sterile medical filters – Overview of the most reliable producers and their products

An overview of manufacturers and its brands of sterile medical membrane filters for biopharmaceutical fluid management.

BRMO

Brian Moloney

December 28, 2021

Fill & Filtration

Medical tubing – Manufacturers, types and materials

An overview of manufacturers and its brands of single-use tubings for biopharmaceutical fluid management.

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David Seifert

December 27, 2021

Fill & Filtration

Sterile Connectors for use in Pharma

An overview of manufacturers and its brands of sterile and aseptic connectors for biopharmaceutical fluid management.

BRMO

Brian Moloney

December 27, 2021

Cell & Gene Therapy

Supply chain optimization in cell and gene therapies

Single Use Support is solving problems related to supply chain management through the development of smart packaging and related smart technologies for CAR T-cell therapy. Read more!

BRMO

Brian Moloney

December 20, 2021

Cell & Gene Therapy

Advanced therapy medicinal products - a new era of medicine

Advanced therapy medicinal products (ATMPs) are medicines for human use that are based on genes, tissues or cells. Accordingly, they can be classified into three main types, namely gene therapy, tissue engineered- and somatic-cell therapy medicines. Read more!

micheal-eder

Michael Eder

December 20, 2021

Single-use Technology

Small volumes of ATMPs: Safe handling of single-use bags

Cell and Gene therapies such as CAR T-cell therapy have proven their potential to become standard treatments to hard-to-treat diseases. Single Use Support has developed solutions for crucial challenges - read more!

michael-muehlegger

Michael Mühlegger

December 2, 2021

Cell & Gene Therapy

Cell and gene therapy: In vivo and Ex vivo in comparison

Gene therapy is a technique that modifies a person’s genes to treat or cure disease. Ex Vivo and In Vivo are two different approaches you will learn about in this article!

michael-muehlegger

Michael Mühlegger

December 2, 2021

Single-use Technology

Protecting single-use bags to foster their progress

Single-use systems are on the rise. And yet there is hesitation to make single-use technologies continue to thrive. Get to know how single-use systems get full acceptance. 

micheal-eder

Michael Eder

November 29, 2021

Recommended Downloads

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eBook: Filling Gaps in Managing Large Volumes of Biologics

Aseptic aliquotation and cryopreservation of drug substances are crucial process steps in bioprocessing. Even though they’re not in the spotlight of biomanufacturing. In drug development and drug delivery, biologics must be transferred at numerous occasions. Along the journey of monoclonal antibodies, vaccines and more, the drug substance passes lots of process steps where liquid transfer is required. This is relevant for the transitions between upstream processing, downstream processing and fill & finish, but also within these manufacturing milestones. The market of fluid & cold chain management has great growth potential and is on its way to professionalization and industrialization. To meet the challenges of manufacturing drug substances, Single Use Support helps manufacturers and CDMOs to advance their fluid & cold chain management process to achieve a secure and efficient process for liquids on the basis of single-use bags.

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Whitepaper: How Controlled & Scalable Freezing Becomes Reality

Scalability around freezing means the ability to guarantee constant freezing kinetics on proteins (biopharmaceutical molecules) in all scales, filling volumes and loading scenarios. This guide covers how to achieve scalable freezing & thawing of biopharmaceuticals by showing What is scalability? Setup for controlled icefront growth speed Scalability results Outcomes

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Whitepaper: Automated Aseptic Filling

Read our Whitepaper about Automated Aseptic Filling in Pharmaceutical Manufacturing | Discover why automatic filling solutions are preferable to manual filling.