Freezing drug substances to ultra-cold temperatures is a standard step in biopharmaceutical manufacturing. Yet, beyond simply cooling, it’s the critical quality attributes (CQA), like product safety, consistency, and process efficiency, that trul...
The adeno-associated virus (AAV) is a very popular viral vector with great potential available for gene delivery. This article explores AAV vectors, their role in gene therapy, and their associated advantages and disadvantages. What is an AA...
On the biopharmaceutical market, plasmid DNA manufacturing companies have become essential players, as pDNA has enabled significant advancements in biotechnology. Whether it’s gene therapy, the development of DNA vaccines, or the production of cel...
Plasmids have multiple functions within bacterial cells and beyond, being powerful tools for modifying genetic material and advancing biotechnological applications. Their discovery in the last century was a tremendous achievement in microbiology a...
Plasmid DNA manufacturing is a process that is crucial in biotechnology and research to enable the production of DNA constructs. Those constructs are used for genetic manipulation and various applications in a number of fields, including molecular...
Plasmid DNA stands as a fascinating topic in the field of molecular biology. This double-stranded nucleic acid molecule is known for its versatility as a genetic vehicle and holds numerous intriguing characteristics. From autonomous replication to...
A plasmid is a small, circular DNA fragment that has received considerable attention due to its capacity to transport and transmit genetic information among different organisms. Nevertheless, they are not only part of the genetic material in bacte...
Modular filling enabling process flexibility for viral vector manufacturing We are thrilled to unveil our latest customized innovation within the product range of automated aliquoting systems, RoSS.FILL. This groundbreaking solution is set to r...
Cryopreservation involves the preservation of cells, tissues, or other biological constructs by cooling them to extremely low temperatures. The preservation of cells at cryogenic temperature can be achieved using different techniques. This is far ...
Cryopreservation describes methods to preserve living organisms and biological materials at very low temperatures. Central to this process is the use of liquid nitrogen, enabling successful cryogenic freezing and cryopreservation, opening possibil...
Cell viability is an important topic in cell banking, as it expresses the amount of healthy cells in a sample and is counted among the most important CQAs (Critical Quality Attributes), determining the quality of biological products. In order to e...
Cell thawing is a critical procedure in the area of life science and medicine. Ensuring a gentle thawing of frozen cells is essential for preserving their viability and functionality. In this article, we will highlight the cell thawing process, di...
Who can relate to the situation when every cell aliquot is different? That's why cell homogenization and aliquotation are important requirements in modern cell biology research, relevant for scientists and laboratory staff. Scientists and process ...
