Bioconjugates
Depending on their constituents, ADCs are extremely variable and can be used for several, very distinct purposes. In this article, we will present you 5 examples of ADCs and their respective characteristics.
Brian Moloney
April 25, 2023
Bioconjugates
ADC technology has revolutionized several fields in medicine and research. In this article, we will shed light on this groundbreaking technology.
Daniel Tischler
April 25, 2023
Bioconjugates
Antibody drug conjugates (ADCs) are a rapidly growing field of interest in biopharmaceutics. In comparison to conventional chemotherapy treatments, ADCs have the potential to destroy cancerous cells without damaging healthy cells in the process. In this article we will give you an introduction to this important and rapidly growing field.
Brian Moloney
April 24, 2023
Bioconjugates
The safe handling of ADCs or other HPAPIs is a complex and elaborate process that requires specialized facilities and a safe, sterile environment. The filling/aliquoting step in particular calls for great care and specific equipment to ensure sterility and rule out any potential cross-contamination as well as potential harm to handling staff.
Brian Moloney
April 24, 2023
Bioconjugates
The manufacturing of bioconjugates is a complex process that involves linking a drug payload with a targeting moiety using a linker. The process is highly specific and requires careful optimization to ensure that the bioconjugate is effective and safe for use in patients. Single-use technology has revolutionized the manufacturing of bioconjugates by offering a range of benefits over traditional stainless-steel manufacturing. Therefore, this article will pay special attention to this subject.
Brian Moloney
April 24, 2023
Bioconjugates
Bioconjugation is a pharmaceutical technique that is gaining more and more importance, most of all in cancer therapy. In this article, we will provide some basic information on bioconjugation, but also discuss major challenges related to this field.
Michael Mühlegger
April 20, 2023
Cell & Gene Therapy
The term "autologous" is most frequently found in the context of cell therapy. In this article, we will therefore take a closer look at this revolutionary therapeutic approach.
Michael Eder
April 20, 2023
Cell & Gene Therapy
What does "allogeneic" mean, precisely? How do allogeneic cell therapies work, and what is the difference to autologous approaches? Questions like these will be answered in this article.
Michael Eder
April 19, 2023
Bioconjugates
Since the first ADCs entered clinical trials in the 1990s, they have shown great promise in treating a variety of cancers and other diseases. However, the development of ADCs has also been marked by challenges and setbacks, including issues with efficacy, safety, and manufacturing. In this article, we will explore the history of ADCs, from their early development to the latest advances in technology and applications.
Michael Eder
April 14, 2023
Bioprocessing
Automation is affecting various aspects of our lives, including bioprocessing. In this article, we will explore the advantages that come with this development.
Michael Mühlegger
April 12, 2023
Freeze & Thaw
Spray drying often leads to product losses of mAbs or vaccines of more than 30%. Plate-based freezing and thawing solutions enable controlled handling of bulk intermediates safely in a vendor-independent, modular and scalable fluid and cold chain management process.
Daniel Tischler
April 12, 2023
Vaccines
The terms "drug substance" and "drug product" are often used synonymously, although there are some fundamental differences between them. We will point them out in the course of this article!
Michael Eder
April 11, 2023
